个人信息（Personal Information）
男，1973.01，教授，河南大学黄河学者特聘教授，有机化学博士，
药剂学带头人，dsf_2007@163.com。手机：17752572059
受教育经历 (Educational Experience)
2002.08-2007.10，新墨西哥州立大学，化学与生物化学系，博士（有机化学）
1998.09-2000.10，华东理工大学，精细化工研究所，攻读博士
1995.09-1998.04，南京理工大学，化工学院，硕士（应用化学）
1991.09-1995.07，南京理工大学，化工学院，本科（精细化工）
工作经历 (Professional Experience)
2015.09-至今，河南大学药学院，教授，黄河学者特聘教授
2010.05-2015.08，美国堪萨斯大学药学院，研究员
2008.11-2010.05，美国堪萨斯大学药学院，博士后
2007.10-2008.11，美国堪萨斯大学化学系，博士后
研究兴趣（Research Interests）
研究方向:(1)小分子药物的设计与合成；(2)纳米高分子药物载体的设计与合成；(3)药物靶向递送及药物控释。
学术任职
[1] Sigma Xi
[2] American Chemical Society
[3] Drug Discoveries & Therapeutics 编委
[4] Molecules 客座编辑
[5] 河南省药学会药物制剂专委会副主任委员
[6] 河南省中药药效国际联合实验室主任
[7] 河南省开封市药学会常务理事、技术部主任
[8] 河南大学创新药物设计与评价研究所所长
专业杂志审稿人
[1] Nanomedicine: Nanotechnology, Biology, and Medicine
[2] Acta Biomaterialia
[3] European Journal of Pharmaceutical Sciences
[4] Pharmaceutical Research
[5] Journal of Pharmaceutical Sciences
[6] Small
[7] Biomacromolecules
[8] Journal of Medicinal Chemistry
承担项目 (Financial Supports)
[1] 基于金纳米棒的新型一氧化氮供体前药的合成及其在抗乳腺癌方面的应用研究，162300410044，10万，2017.01-2019.12，河南省自然科学基金，主持。
[2] 河南大学黄河学者启动基金， 50万元，2015.09-2020.08，河南省博士后科研项目，主持。
[3] 新型前列腺癌靶点p110β精准抑制剂的构效研究和机制探索，212102311025，河南省重点研发与推广专项 （科技攻关）（the Key Research and Development Projects of Henan Province），2021.01-2022.12，主持。
[4] 温敏性透明质酸水凝胶的构建及其负载药物、子宫内膜干细胞联合治疗宫腔粘连的作用评价，222102310453，河南省重点研发与推广专项 （科技攻关）（the Key Research and Development Projects of Henan Province），2022.01-2023.12，主持。
[5] 多靶向金纳米-温敏脂质体复合纳米粒介导的化热疗及基因疗对乳腺癌靶向特异性治疗研究，232102311170，10万元，河南省重点研发与推广专项 （科技攻关）（the Key Research and Development Projects of Henan Province），2023.01-2024.12，主持。
[6]
代表性论著 (Publications, 共69篇)
[1] Tingkui Zhao; Fujin He; Keqing Zhao; Lin Yuxia; Huanyu Li; Xingru Liu; Juan Cen*; Shaofeng Duan*. A Triple-Targeted Rutin-Based Self-Assembled Delivery Vector for Treating Ischemic Stroke by Vascular Normalization and Anti-Inflammation via ACE2/Ang17 Signaling. ACS Central Science 2023, 9, 6, 1180-1199. doi/10.1021/acscentsci.3c00377.
[2] Shengnan Huang, Chengzhi Song, Jinxin Miao, Xiali Zh, Yongyan Jia, Yafei Liu, Dongjun Fu, Benyi Li, Mingsan Miao, Shaofeng Duan*, Zhenzhong Zhang*, Yurong Hu*. Red blood cell membrane-coated functionalized Au nanocage as a biomimetic platform for improved MicroRNA delivery in hepatocellular carcinoma. International Journal of Pharmaceutics 2023, 642:123044
[3] Shaofeng Duan#, Yifan Xia#, Xue Tian#, Jie Cui, Xin Zhang, Qian Yang, Tingkui Zhao, Yuxia Lin, Feng Zhang*, Xiaoju Zhang*, Juan Cen*. Construction of multi-bioreactive self-assembled nano-drug delivery system based on geraniol and evaluation of its anti-tumor effect on liver cancer. Carbohydrate Polymers 2023, 310, 120695.
[4] Xuanping Zhao, Chuan Liu, Zichao Wang, Yingyuan Zhao, Xuyang Chen, Haizhen Tao, Hong Chen, Xueqin Wang*, Shaofeng Duan*. Synergistic Pro-Apoptotic Effect of a Cyclic RGD Peptide-Conjugated Magnetic Mesoporous Therapeutic Nanosystem on Hepatocellular Carcinoma HepG2 Cells. Pharmaceutics 2023, 15(1), 276.
[5] Xuyang Chen, Haizhen Tao, Yuqi Guo, Zichao Wang, Ruifang Li, Yingyuan Zhao, Chuan Liu, Xuanping Zhao, Xueqin Wang*, Shaofeng Duan*. Anti-CD44 antibodies grafted immunoaffinity Fe3O4@MnO2 nanozymes with highly oxidase-like catalytic activity for specific detection of triple-negative breast cancer MDA-MB-231 cells. Analytica Chimica Acta 2023, 1249: 340947.
[6] Yurong Hu*, Lixiao Chen, Mengkang Liu, Zijun Ma, Chenyang Zhou, Zhiwei Yao, Shuhao Zhang, Chengzhi Song, Zhihao Wang, Xiali Zhu, Mingsan Miao, Shaofeng Duan*, Shengnan Huang*. Multifunctional immunotherapeutic gel prevented postoperative recurrence of hepatocellular carcinoma Multifunctional immunotherapeutic gel prevented postoperative recurrence of hepatocellular carcinoma. Chemical Engineering Journal 2023, 457:141124.
[7] Liu, Chang; Wang, Zhenxing; Liu, Qian; Wu, Guangyao; Chu, Chunhong; Li, Lanxin; An, Lei*; Duan, Shaofeng*. Sensitivity analysis of EGFR L861Q mutation to six tyrosine kinase inhibitors. Clinical and Translational Oncology 2022, 24(10), 1975-1985.
[8] Lingling Jiang†, Han Yu†, Chenwei Wang, Fujin He, Zhongqi Shi, Haohong Tu, Na Ning, Shaofeng Duan*, Yunqi Zhao*. The Anti-Cancer Effects of Mitochondrial-Targeted Triphenylphosphonium–Resveratrol Conjugate on Breast Cancer Cells. Pharmaceuticals 2022, 15, 1271.
[9] Cen, Juan; Zhang, Runfang; Zhao, Tingkui; Zhang, Xin; Zhang, Chuan; Cui, Jie; Zhao, Keqing; Duan, Shaofeng*; Guo, Yuqi*. A Water-Soluble Quercetin Conjugate with Triple Targeting Exerts Neuron-Protective Effect on Cerebral Ischemia by Mitophagy Activation. Advanced Healthcare Materials 2022 11(22): 2200817
[10] Cen, Juan; Zhang, Yichen; Bai, Yindu; Ma, Shenqian; Zhang, Chuan; Jin, Lin; Duan, Shaofeng*; Du, Yanan; Guo, Yuqi. Research progress of stem cell therapy for endometrial injury. Materials Today Bio 2022, 16, 100389.
[11] Shao-Feng Duan, Meng-Meng Zhang, Xin Zhang, Wei Liu, Shi-Hui Zhang, Bo Yang, Qian Dong, Ju-Guo Han, Hai-Lan Yu, Tao Li, Xin-Ying Ji**, Dong-Dong Wu*, Xiao-Ju Zhang***. HA-ADT suppresses esophageal squamous cell carcinoma progression via apoptosis promotion and autophagy inhibition. Experimental Cell Research 2022, 420:113341.
[12] Haizhen Tao, Xuyang Chen, Ruifang Li, Zichao Wang, Xuanping Zhao, Chuan Liu, Shaofeng Duan*, Xueqin Wang**. A flexible visual detection of calcium peroxide in flour employing enhanced catalytic activity of heterogeneous catalysts binary copper trapped silica-layered magnetite nanozyme. Colloids and Surfaces B: Biointerfaces 2022, 219:112823.
[13] Xianyou Wang, Mingzhu Li, Yun Bai, Yaowu Du*, Shaofeng Duan**. Non-holostane and holostane triterpene glycosides from spawn of sea cucumber Apostichopus japonicus selenka. Journal of Food Composition and Analysis 2022, 109: 104492.
[14] Zhang, Xiaowan; Yang, Yixin; Qin, Peige; Han, Lizhen; Zhu, Wenli; Duan, Shaofeng; Lu, Minghua; Cai, Zongwei. Facile preparation of nano-g-C3N4/UiO-66-NH2 composite as sorbent for high-efficient extraction and preconcentration of food colorants prior to HPLC analysis. Chinese Chemical Letters 2022, 33(2), 903-906.
[15] Xueqin Wang, Tiandi Xiong, Miao Cui, Na Li, Qin Li, Li Zhu, Shaofeng Duan*, Yunlong Wang* and Yuqi Guo*. A novel targeted co delivery nanosystem for enhanced ovarian cancer treatment via multidrug resistance reversion and mTOR mediated signaling pathway. Journal of Nanobiotechnology 2021, 19:444
[16] Liu, Yantao; Zhu, Keyong; Kong, Yuting; Li, Xiao; Cui, Jie; Xia, Yifan; Zhao, Jingjing; Duan, Shaofeng*; Li, Pan*. Merging Gold/Copper Catalysis and Copper/Photoredox Catalysis: An Approach to Alkyl Oxazoles from N-Propargylamides. Journal of Organic Chemistry 2021, 86(24), 18247-18256.
[17] Runfang Zhang, Tingkui Zhao, Beibei Zheng, Yun Zhang, Xiaohui Li, Feng Zhang*, Juan Cen*, Shaofeng Duan*. Curcumin Derivative Cur20 Attenuated Cerebral Ischemic Injury by Antioxidant Effect and HIF-1α/VEGF/TFEB-Activated Angiogenesis. Frontiers in Pharmacology 2021, 12: 648107.
[18] Miao Cui, Hui-Ru Zhang, Fan Ouyang, Yu-Qi Guo, Rui-Fang Li, Shao-Feng Duan*, Tian-Di Xiong, Yun-Long Wang∗, and Xue-Qin Wang∗.Dual Enzyme-Like Performances of PLGA Grafted Maghemite Nanocrystals and Their Synergistic Chemo/Chemodynamic Treatment for Human Lung Adenocarcinoma A549 Cells. Journal of Biomedical Nanotechnology 2021, 17: 1-13.
[19] Qiao, Yonghui; Wei, Zhihao; Qin, Tingting; Song, Rufeng; Yu, Zhiqiang; Yuan, Qi; Du, Juan; Zeng, Qingbing*; Zong, Lanlan*; Duan, Shaofeng*, Pu Xiaohui*. Combined nanosuspensions from two natural active ingredients for cancer therapy with reduced side effects. Chinese Chemical Letters 2021, (9):2877-2881.
[20] Ngowi EE, Wang Y-Z, Qian L, Helmy YASH, Anyomi B, Li T, Zheng M, Jiang E-S, Duan S-F, Wei J-S, Wu D-D and Ji X-Y. The Application of Nanotechnology for the Diagnosis and Treatment of Brain Diseases and Disorders. Front. Bioeng. Biotechnol. 2021, 9:629832.
[21] Khattak S, Zhang X, Li T, Duan S-F, Ji X-Y and Wu D-D. Roles of Hydrogen Sulfide Donors in Common Kidney Diseases. Front. Pharmacol. 2020, 11:564281.
[22] Ebenezeri Erasto Ngowi, Attia Afzal, Muhammad Sarfraz, Saadullah Khattak, Shams Uz Zaman, Nazeer Hussain Khan, Tao Li, Qi-Ying Jiang, Xin Zhang, Shao-Feng Duan*, Xin-Ying Ji*, Dong-Dong Wu*. Role of hydrogen sulfide donors in cancer development and progression. International Journal of Biological Sciences 2021; 17(1): 73-88.
[23] Yan, Guoyi; Li, Dongxiao; Zhong, Xinxin; Liu, Ge; Wang, Xueqin; Lu, Yuanxiang; Qin, Fangyuan; Guo, Yuqi; Duan, Shaofeng; Li, Deyu. Identification of HDAC6 selective inhibitors: pharmacophore based virtual screening, molecular docking and molecular dynamics simulation. Journal of Biomolecular Structure and Dynamics 2021, 39(6), 1928-1939.
[24] Xueqin Wang∗, Tiandi Xiong, Miao Cui, Xinglei Guan, Jiacheng Yuan, Zichao Wang, Ruifang Li, Huiru Zhang, Shaofeng Duan∗, Fang Wei∗.Targeted self-activating Au-Fe3O4 composite nanocatalyst for enhanced precise hepatocellular carcinoma therapy via dual nanozyme-catalyzed cascade reactions. Applied Materials Today 2020, 21,100827
[25] Wang, Xueqin; Lu, Ping; Zhu, Li; Qin, Li; Zhu, Yongxia; Yan, Guoyi; Duan, Shaofeng*; Guo, Yuqi. Active Targeting Co-delivery of Therapeutic Sur siRNA and Antineoplastic Drug via Epidermal Growth Factor Receptor Mediated Magnetic Nanoparticles for Synergistic Programmed Cell Death in Glioblastoma Stem Cells. Materials Chemistry Frontiers 2020, 4, 574-588.
[26] Ebenezeri Erasto Ngowi, Muhammad Sarfraz, Attia Afzal, Nazeer Hussain Khan, Saadullah Khattak, Xin Zhang, Tao Li, Shao-Feng Duan*, Xin-Ying Ji* and Dong-Dong Wu*. Roles of Hydrogen Sulfide Donors in Common Kidney Diseases. Front. Pharmacol., 2020 doi.org/10.3389/fphar.2020.564281.
[27] Attia Afzal; Muhammad Sarfraz; Guang-Lei Li; Shao-Ping Ji; Shao-Feng Duan; Nazeer Hussain Khan; Dong-Dong Wu*; Xin-Ying Ji*. Taking a holistic view of PEST-containing nuclear protein (PCNP) in cancer biology. Cancer Medicine 2019, 8:6335-6343.
[28] Wang, Xueqin; Lu, Ping; Zhu, Li; Qin, Li; Zhu, Yongxia; Yan, Guoyi; Duan, Shaofeng*; Guo, Yuqi. Anti-CD133 Antibody-Targeted Therapeutic Immunomagnetic Albumin Microbeads Loaded with Vincristine-Assisted to Enhance Anti-Glioblastoma Treatment. Molecular Pharmaceutics 2019, 16(11), 4582-4593.
[29] Wang, Xueqin; Ouyang, Fan; Cui, Liuqing; Xiong, Tiandi; Guan, Xinglei; Guo, Yuqi*; Duan, Shaofeng*. Surface coating-modulated peroxidase-like activity of maghemite nanoparticles for a chromogenic analysis of cholesterol. Journal of Nanoparticle Research 2019, 21(10), 1-13.
[30] Dong, Qian; Yang, Bo; Han, Ju-Guo; Zhang, Meng-Meng; Liu, Wei; Zhang, Xin; Yu, Hai-Lan; Liu, Zheng-Guo; Zhang, Shi-Hui; Li, Tao; Dong‐Dong Wu*; Xin-Ying Ji*; Shao-Feng Duan*. A novel hydrogen sulfide-releasing donor, HA-ADT, suppresses the growth of human breast cancer cells through inhibiting the PI3K/AKT/mTOR and Ras/Raf/MEK/ERK signaling pathways. Cancer Letters 2019, 455, 60-72.
[31] Fengqian Guo#,Chunyu Yang#, Yue Shang, Chen Zang, Baoxian Zhang, Hailan Yu, Cui Li*；Shao-Feng Duan*. Comparison of the quality of Chinese Ginger Juice powders prepared by different drying methods. Journal of Food Process Engineering 2019, 42:e13252.
[32] Yan, Li-Juan; Guo, Xin-Hong; Wang, Wei-Ping; Hu, Yu-Rong*; Duan, Shao-Feng*; Liu, Ying; Sun, Zhi; Huang, Sheng-Nan; Li, Hui-li. Gene Therapy and Photothermal Therapy of Layer-by-Layer Assembled AuNCs /PEI/miRNA/ HA Nanocomplexes. Current Cancer Drug Targets 2019, 19(4), 330-337.
[33] Dong-Dong Wu, Da-Yong Wang, Hui-Min Li Jian-Cheng Guo, Shao-Feng Duan*, Xin-Ying Ji*. Hydrogen sulfide as a novel regulatory factor in liver health and disease. Oxidative Medicine and Cellular Longevity 2019 (5), 1-16.
[34] Dong‐Dong Wu, Shi‐Yu Liu, Ying‐Ran Gao, Dan Lu, Ya Hong, Ya‐Ge Chen, Peng‐Zhen Dong, Da‐Yong Wang, Tao Li, Hui‐Min Li, Zhi‐Guang Ren, Jian‐Cheng Guo, Fei He, Xue‐Qun Ren, Shi-Yong Sun, Shao‐Feng Duan*, Xin‐Ying Ji*. Tumour necrosis factor‐α‐induced protein 8‐like 2 is a novel regulator of proliferation, migration, and invasion in human rectal adenocarcinoma cells. J Cell Mol Med. 2019, 23(3), 1698-1713.
[35] Li, Huili; Li, Huanjie; Yu, Wei; Huang, Shengnan; Liu, Ying; Zhang, Ningxia; Yuan, Jinxiu; Xu, Xin; Duan, Shaofeng*; Hu, Yurong*. PEGylated hyaluronidase/NIR induced drug controlled release system for synergetic chemo-photothermal therapy of hepatocellular carcinoma. European Journal of Pharmaceutical Sciences 2019, 133, 127-136.
[36] Cui Li, Chen Zang, Qixia Nie, Bo Yang, Baoxian Zhang, Shaofeng Duan*. Simultaneous determination of seven flavonoids, two phenolic acids and two cholesterines in Tanreqing injection by UHPLC-MS/MS. Journal of Pharmaceutical and Biomedical Analysis 2019, 163, 105-112.
[37] Wang, Weiping; Huang, Shengnan; Yuan, Jinxiu; Xu, Xin; Li, Huili; Lv, Zhanwei; Yu, Wei; Duan, Shaofeng*; Hu, Yurong*. Reverse multidrug resistance in human HepG2/ADR by anti-miR-21 combined with hyperthermia mediated by functionalized gold nanocages. Molecular Pharmaceutics 2018, 15(9), 3767-3776.
[38] Yanping Cao, Zhihao Wei, Mengmeng Li, Haiyan Wang, Li Yin, Dongxiao Chen, Yanfei Wang,Yongchao Chen, Qi Yuan, Xiaohui Pu*, Lanlan Zong*, Shaofeng Duan*. Formulation, pharmacokinetic evaluation and cytotoxicity of an enhanced-penetration paclitaxel nanosuspension. Current Cancer Drug Targets 2019 19(4), 338-347.
[39] Pu, Xiaohui; Li, Jia; Qiao, Peng; Li, Mengmeng; Wang, Haiyan; Zong, Lanlan; Yuan, Qi; Duan, Shaofeng*. Mesoporous Silica Nanoparticles as a Prospective and Promising Approach for Drug Delivery and Biomedical Applications. Current Cancer Drug Targets 2019, 19(4), 285-295.
[40] Wang Da-Yong; Wang Da-Yong; Hong Ya; Chen Ya-Ge; Dong Peng-Zhen; Liu Shi-Yu; Gao Ying-Ran; Lu Dan; Li Hui-Min; Li Tao; Dong‐Dong Wu*; Xin-Ying Ji*；Shao-Feng Duan*. PEST-containing nuclear protein regulates cell proliferation, migration, and invasion in lung adenocarcinoma. Oncogenesis 2019, 8(3), 22.
[41] Li, Changlin; He, Chenchen; Xu, Ying; Xu, Haixia; Tang, Yuzhe; Chavan, Hemantkumar; Duan, Shaofeng; Artigues, Antonio; Forrest, Marcus Laird; Krishnamurthy, Partha; et al. Alternol eliminates excessive ATP production by disturbing Krebs cycle in prostate cancer. Prostate 2019, 79(6), 628-639.
[42] Guo-Yu Zhang#, Dan Lu#, Shao-Feng Duan#, Ying-Ran Gao, Shi-Yu Liu, Ya Hong Peng-Zhen Dong, Ya-Ge Chen, Tao Li, Da-Yong Wang, Xiang-Shu Cheng, Fei He Jian-She Wei, Guang-Yu Li, Qing-Yong Zhang, Dong-Dong Wu. Hydrogen Sulfide Alleviates Lipopolysaccharide-Induced Diaphragm Dysfunction in Rats by Reducing Apoptosis and Inflammation through ROS/MAPK and TLR4/NF-κB Signaling Pathways. Oxidative Medicine and Cellular Longevity 2018, 9647809.
[43] Dongdong Wu, Honggang Wang, Tieshan Teng, Shaofeng Duan, Ailing Ji, Yanzhang Li. Hydrogen sulfide and autophagy: A double edged sword. Pharmacological Research 2018, 131, 120-127.
[44] Huang, Shengnan; Liu, Ying; Xu, Xin; Ji, Mengfei; Li, Yuanmin; Song, Chengjun; Duan, Shaofeng*; Hu, Yurong*. Triple therapy of hepatocellular carcinoma with microRNA-122 and doxorubicin co-loaded functionalized gold nanocages. Journal of Materials Chemistry B: Materials for Biology and Medicine 2018, 6(15), 2217-2229.
[45] Mengfei Ji, Xiaojing Qiu, Lin Hou, Yuanmin Li, Shengnan Huang, Yang Liu, Shaofeng Duan*, Yurong Hu*. Construction and Application of a Liver Cancer-targeting drug Delivery System Based on Core-shell Gold Nanocages. International Journal of Nanomedicine 2018, 13, 1773-1789.
[46] Shijin Bao, Shengnan Huang, Ying Liu, Yurong Hu*, Weiping Wang, Mengfei Ji, Huili Li, Ningxia Zhang, Chengzhi Song, Shaofeng Duan*. Gold nanocages with dual modality for image guided therapeutics. Nanoscale 2017, 9, 7284-7296.
[47] Li, Mengmeng; Chen, Yongchao; Yin, Li; Wang, Haiyan; Cao, Yanping; Wei, Zhihao; Wang, Yanfei; Yuan, Qi; Pu, Xiaohui; Zong, Lanlan; Duan, Shaofeng. Formulation and stability evaluation of structure-altered paclitaxel nanosuspensions stabilized by a biocompatible amino acid copolymer. Science of Advanced Materials 2017, 9(10), 1713-1723.
[48] Chenchen He, Shaofeng Duan, Liang Dong, Yifen Wang, Qingting Hu, Chunjing Liu, Marcus L. Forrest, Jeffrey M. Holzbeierlein, Suxia Han, Benyi Li. Characterization of a novel p110β-specific inhibitor BL140 that overcomes MDV3100-resistance in castration-resistant prostate cancer cells. Prostate 2017, 77(11):1187-1198.
[49] Shengnan Huang, Chunming Li, Weiping Wang, Huanjie Li, Zhi Sun, Chengzhi Song, Shaofeng Duan*, Yurong Hu*, Benyi Li. A54 peptide-mediated functionalized gold nanocages for targeted delivery of DOX as a combinational chemo-photothermal therapy for hepatocellular carcinoma. International Journal of Nanomedicine 2017, 12, 5163-5176.
[50] Shengnan Huang#, Shaofeng Duan#, Jing Wang, Shijin Bao, Xiaojing Qiu, Chunming Li, Ying Liu, Lijuan Yan, Zhenzhong Zhang, Yurong Hu*. Folic Acid Mediated Functionalized Gold Nanocages for Targeted Delivery of Anti-miR-181b in Combination of Gene Therapy and Photothermal Therapy against Hepatocellular Carcinoma. Advanced Functional Materials 2016, 26(15), 2532-2544 (first co-author).
[51] Solomon Z Okbazghi, Apurva S More, Derek R White, Shaofeng Duan, Ishan S Shah, Sangeeta B Joshi, C Russell Middaugh, David B Volkin, Thomas J Tolbert. Production, Characterization, and Biological Evaluation of Well-Defined IgG1 Fc Glycoforms as a Model System for Biosimilarity Analysis. J Pharm Sci 2016, 105(2), 559-74.
[52] Yunqi Zhao, Ti Zhang#, Shaofeng Duan#, Neal M Davies, M Laird Forrest. CD44-tropic polymeric nanocarrier for breast cancer targeted rapamycin chemotherapy. Nanomedicine 2014, 10(6), 1221-30.
[53] Lohrman, Jessica; Liu, Yueying; Duan, Shaofeng; Zhao, Xiaoyong; Wuttig, Manfred; Ren, Shenqiang; All Conjugated Copolymer Excitonic Multiferroics. Advanced Materials 2013, 25 (5), 783-787.
[54] Ndolo, Rosemary A.; Luan, Yepeng; Duan, Shaofeng; Forrest, M. Laird; Krise, Jeffrey P. Lysosomotropic properties of weakly basic anticancer agents promote cancer cell selectivity in vitro. PLoS One 2012, 7(11), e49366.
[55] SM Cohen, R Mukerji, S Duan, S Cai, ML Forrest, MS CohenM. Laird Forrest. A Novel Nanocarrier Delivery System for Doxorubicin with Improved Tumor Response and Reduced Systemic Toxicity in Advanced Pediatric Non-Hodgkin Lymphoma. Journal of Surgical Research. 2012, 172 (2), 317.
[56] Yunqi Zhao#, Shaofeng Duan#, Xing Zeng, Chunjing Liu, Benyi Li, Neal M. Davies, M Laird Forrest. Prodrug Strategy for PSMA-targetted Delivery of TGX-221 to Prostate Cancer Cells. Molecular Pharmaceutics 2012, 9, 1705−1716 (first co-author).
[57] Taryn R. Bagby#, Shaofeng Duan#, Shuang Cai, Laird Forrest. Functional lymphatic imaging using negatively charged star polymer architectures grafted with near-infrared dye. European Journal of Pharmaceutical Sciences 2012, 47(1), 287-294 (first co-author).
[58] Taryn R. Bagby, Shuang Cai, Shaofeng Duan, Sharadvi Thati, Aires, Daniel J., Laird Forrest. Impact of molecular weight on lymphatic drainage of a biopolymer-based imaging agent. Pharmaceutics 2012, 4(2), 276-295.
[59] Shaofeng Duan, Shuang Cai, Yumei Xie, M. Laird Forrest. Ester star polymers as controlled drug release carriers for cisplatin and nitric oxide. Journal of Polymer Science Part A: Polymer Chemistry 2012, 50, 2715–2724.
[60] Shaofeng Duan, Shuang Cai, Qiuhong Yang, M. Laird Forrest. Multi-arm polymeric nanocarrier as a nitric oxide delivery platform for chemotherapy of head and neck squamous cell carcinoma. Biomaterials 2012, 33, 3243-3253.
[61] Yepeng Luan, Qiuhong Yang, Yumei Xie, Shaofeng Duan, M.L Forrest. A Sensitive Near-Infrared Fluorescent Probe for Caspase-mediated Apoptosis: Synthesis and Application in Cell Imaging. Drug Discoveries & Therapeutics 2011, 5(5), 220-226.
[62] Rajesh Kumar Patti, Shaofeng Duan, Zhipeng Wang, James W. Herndon. Preparation of phenalenes and hydronaphthacenes through tandem alkyne Fischer–carbene complex coupling and inter- or intra-molecular Diels–Alder reactions. Tetrahedron Lett. 2011, 52(32), 4182-4185.
[63] Rajesh Kumar-Patti, Shaofeng Duan, Alejandro Camacho-Davila, Kris Waynant, Kenneth A Dunn, James W Herndon. Synthesis of hydronaphthalenes through coupling of enyne carbonyl compounds that contain pendant alkene groups with Fischer carbene complexes. Tetrahedron Lett. 2010, 51(28), 3682-3684.
[64] Xie, Yumei; Duan, Shaofeng; Forrest, M. Laird. Alkyne- and 1, 6-elimination-succinimidyl carbonate-terminated heterobifunctional poly (ethylene glycol) for reversible "click" PEGylation. Drug Discoveries & Therapeutics 2010, 4(4), 240-245.
[65] Sandipan Sinha, Lei Zhang, Shaofeng Duan, Todd Williams, Josef Vlasak, Roxana Lonescu, Elizabeth Topp. Effect of protein structure on deamidation rate in the Fc fragment of an IgG1 monoclonal antibody. Protein Science 2009, 18(8), 1573-1584.
[66] Shaofeng Duan, Ranjan Jana, Jon Tunge. “Lewis acid-catalyzed diastereoselective hydroarylation of benzylidene malonic esters” J. Org. Chem. 2009, 74, 4612-4614.
[67] Shaofeng Duan, Dilip K. Sinha-Mahapatra, James W. Herndon. “Synthesis of Nanphthalenes through three-component coupling of alkynes, Fischer carbene complexes and Benzaldehyde Hydrozones via Isoindole intermediates” Org. Lett. 2008, 10, 1541-1544.
[68] Shaofeng Duan, Karen Cress, Kris Waynant, Elias Ramos-Miranda, James W. Herndon. “Synthesis of alkylidenephthalans through fluoride-induced cyclization of electron-deficient 2-siloxymethylphenylacetylene derivatives” Tetrahedron 2007, 63, 2959-2965.
[69] Binay K.Ghorai, Shaofeng Duan, Delu jiang, James W. Herndon. “Coupling of β-Cyanocarbene-Chromium Complexes with 2-Alkynylbenzoyl Derivatives: A (5+5)-Cycloaddition Approach to Phenanthridines” Synthesis 2006, 21, 3661-3669.
[70] 夏一帆,崔杰,黄方,张文典*,段少峰*.透明质酸与香叶醇缀合物的合成及其抗肝癌活性[J].中国药学杂志,2023,58(17):1589-1596.
[71] 李肖寒;程雪丹;张智博;胡博凯;段少峰.绿原酸缀合物HA-CGA的抗菌活性研究[J].中国抗生素杂志,2023,48(01):49-53.
[72] 崔杰,夏一帆,张文典*,段少峰*. 花生五烯酸与透明质酸接枝物的合成及其抗肝癌活性[J]. 中国药科大学学报,2022,53(1):46-53.
[73] 张文典,崔杰,夏一帆,段少峰*. 叶酸靶向anti-miR-221阴离子脂质体的制备及体外抗肿瘤作用[J]. 中国药房,2022,33(7):813-817.
[74] 张文典,崔杰,夏一帆,张欣,段少峰*. 两种叶酸偶联物的合成及体外靶向性研究[J]. 中国药科大学学报,2021,52(4):447-454.
专利（Patents）
[1] 段少峰，岑娟，白银都，崔杰，夏一帆。一种聚合物-脂质偶联物及其制备方法和应用(202210048895.0）
[2] 段少峰，岑娟，夏一帆，白银都，崔杰。透明质酸-香叶醇聚合物前药多生物响应的给药系统HSSG NPs及其制备方法和应用(ZL 202210100124.1）
[3] 段少峰，岑娟，白银都，崔杰，夏一帆。花生五烯酸-透明质酸缀合物及其制备方法和应用(202210104413.9）
[4] 段少峰，岑娟，夏一帆，崔杰，刘蒙丽，张欣。一种硫化氢释放剂的荧光衍生物IR780-HA-ADT及其制备方法和应用 (ZL 202110815501.5）
[5] 岑娟，段少峰，李肖寒，张欣，张润芳。靶向脑缺血区线粒体的神经保护药物SS31-HA-QT及其荧光探针和应用 (ZL 202110811352.5）
[6] 段少峰，岑娟，赵廷魁，代晓莹，张欣。一种脑靶向的神经保护剂SS31-HA-RT及其制备方法和应用 (ZL 202110811234.4)
[7] 岑娟，段少峰，崔杰，刘蒙丽，石中奇。一种线粒体靶向的神经保护药物TPP-QT及其制备方法和应用 (ZL 202110814964.X）
[8] 段少峰，岑娟，李肖寒。一种绿原酸缀合物及其制备方法和应用(ZL 202110959220.7）
[9] 田原僮; 陈冠宇; 陈智朋; 钟毅，段少峰。含铜铁氧体纳米粒子、其制备方法及在制备抗菌剂中的应用(CN 111773248 A）
[10] 段少峰，吴东栋，余海兰，韩举国等。一种芦丁螯合物及其制备方法和应用(ZL 201811450594.0）
[11] 段少峰，吴东栋，董茜，韩举国等。 一种硫化氢释放剂HA-ADT、其制备方法及应用. (ZL 201811466003.9）
[12] 胡玉荣; 段少峰等。用于肿瘤疾病早期诊断的试剂盒、检测方法及应用 CN 107893101A）
[13] 张国瑜，李涛，段少峰等。一种基于干细胞源外泌体的组合物及其在制备治疗心肌梗死的药物中的应用 (CN 107137700 A)
[14] Forrest, Marcus Laird, Zhang, Ti, Senadheera, S. P. Sanjeewa N., Aires, Daniel, Zhao, Yunqi, Duan, Shaofeng, Groer, Chad. TARGETED MTOR INHIBITOR (US 20160279108 (A1) - 2016-09-29)
[15] M. Laird Forrest*, Shaofeng Duan, Shuang, Cai, Ti Zhang, Qiuhong Yang. Drug and imaging agent delivery compositions and methods. (WO2013109907 (A1) -2013-07-25)
学术活动
[1] 河南理工大学医学院 《针对肿瘤及脑部疾病的靶向纳米递送系统的开发与研究》， 2023年11月14日
[2] 河南省人民医院 博士沙龙 《几种药物载体的设计，合成及其在抗肿瘤方面的应用》， 2017年11月08日.
[3] 2017年河南省药物制剂创新发展学术研讨会 （河南省漯河市）-主持，2017年6月16-17日.
[4] Duan, Shaofeng, Forrest, M. Laird. Synthesis of sugar and carbonate star polymers for localized chemotherapy. 2015年河南省要药学会学术年会 2015年9月18-19日.
[5] Duan, Shaofeng, Forrest, M. Laird. Synthesis of sugar and carbonate star polymers for localized chemotheraphy. School of Pharmaceutical Sciences at Henan University. June 14, 2014.
[6] Duan, Shaofeng, Forrest, M. Laird. Synthesis of sugar and carbonate star polymers for localized chemotheraphy. School of Pharmaceutical Sciences at Zhengzhou University. July 3, 2013.
[7] M. Laird Forrest, Shuang Cai, Shaofeng Duan, Mark Steven Cohen, Qiuhong Yang. Nitric oxide-releasing nanoparticle combination therapy to overcome drug resistance in platinum-resistant breast cancers. The Breast Cancer Symposium, American Society of Clinical Oncology annual meeting (September 8-10, 2011).
[8] Duan, Shaofeng; Cai, Shuang; Bagby, Taryn R.; Forrest, M. Laird. Synthesis of sugar and carbonate star polymers for localized chemotheraphy. Abstracts, 45th Midwest Regional Meeting of the American Chemical Society, Wichita, KS, United States, October 27-30 (2010), MWRM-428.
[9] Wiget, Paul A.; Mahapatra, Dilip S.; Duan, Shaofeng; Yang, Yan; Herndon, James W. Stereoselectivity in the 8&2 cycloaddition reaction. Abstracts of Papers, 239th ACS National Meeting, San Francisco, CA, United States, March 21-25, (2010), ORGN-522.
[10] Shaofeng Duan, Thomas S. Reynolds, Sandipan Sinha, Mette Thing, Elizabeth M. Topp, Todd Williams. Predicting protein aggregation in amorphous solids using hydrogen/deuterium exchange with mass spectrometry. 2009 AAPS Annual Meeting and Exposition 11/7/2009 - 11/12/2009.
[11] Forrest, M. Laird; Duan, Shaofeng. Development of Structured Star Polymers for Treatment of Locally Advanced Cancers. Abstracts, 44th Midwest Regional Meeting of the American Chemical Society, Iowa City, IA, United States, October 21-24 (2009), MWRM-343.
[12] Herndon, James W.; Kumar-Patti, Rajesh; Ranchigoda-Gamage, Lalith; Duan, Shaofeng; Waynant, Kris; Sinha-Mahapatra, Dilip; Wang, Zhipeng; Li, Rongti; Camacho-Davila, Alejandro; Nelson, Alfreda. The [5+5]-Route for Hydronaphthalene Ring Synthesis Using Fischer Carbenes and Highly Conjugated Alkynes. Abstracts, 65th Southwest Regional Meeting of the American Chemical Society, El Paso, TX, United States, November 4-7 (2009).
[13] Sinha-Mahapatra, Dilip; Duan, Shaofeng; Waynant, Kristopher; Wiget, Paul; Ramos-Miranda, Elias; Wang, Zhipeng; Herndon, James W. Development of Novel Furan Based Cycloadditions. Abstracts, 63rd Southwest Regional Meeting of the American Chemical Society, Lubbock, TX, United States, November 4-7 (2007), GEN-148.
讲授课程：
本科生：《药用高分子材料学》；《药物制剂实验》；《药用递送原理及应用》；《纳米技术与药物制剂》
研究生：《Application of Nanotechnology in Drug delivery》；《专业英语》
教授
当前位置: