人才队伍

基本信息：

戚建平，出生年月为1983年2月，博士，教授，博士生导师，药学院副院长，上海市浦江人才计划，现工作于复旦大学药学院药剂教研室智能化递药教育部重点实验室。 

教育经历

2004.9-2009.7   中国药科大学，药剂学，博士

2000.9-2004.7   中国药科大学，药物制剂，学士

工作经历

2023.4-今       复旦大学药学院，副院长

2022.9-2023.4    复旦大学药学院，药剂系副主任

2018.1 -2023.4   复旦大学药学院，院长助理（教学）

2014.12-今      复旦大学药学院，副教授，教授，博士生导师

2015.3-2016.3    University of California at Santa Barbara，访问学者

2009.7-2014.12   复旦大学药学院，讲师

研究方向

口服给药系统及吸收机制、生物技术药物新剂型、经皮给药系统

联系方式：

电话：021-51980084

手机：15921581816

Email：qijianping@fudan.edu.cn

学术兼职

1.Frontiers in Drug Delivery副主编（口服递送）

2.International Journal of Pharmaceutics, Pharmaceuticals，Chinese Chemical Letters编委

3.国家自然基金委员会外审专家

4.教育部高等学校药学类专业认证专家

5.中国医药生物技术协会纳米生物技术委员会，委员

6.中国药学会纳米药物专委会，青年委员

7.中国颗粒协会，青年理事

8.中国颗粒协会药物制剂及粒子设计专委会，委员

9.中国实验动物学会屏障医学专委会，常务委员

10.中国整形美容协会形塑与综合技术转化分会，常务理事

获奖与荣誉

1.上海市浦江人才计划

2. 2017年全国高等学校药学类专业青年教师微课教学大赛，一等奖

3. 2017年全国高等学校药学类专业青年教师教学能力大赛，一等奖

4. 2020年第一届全国药学专业学位研究生教育教学成果一等奖（排名第三）

5. 复旦大学港爱奖教金

6. 复旦大学第一三共奖教金

科研课题（纵向）

1.主持，国家自然科学基金面上项目（82073801），基于共熔原理的“生物溶剂”促进药物溶解和渗透作用及机制研究，2021.1-2024.12.

2.主持，国家自然科学基金面上项目（81872826），新型“水淬灭”近红外荧光探针的设计及其在纳米粒体内过程研究中的应用，2019.1-2022.12.

3.主持，上海市浦江人才计划（18PJD001），基于跨“穹顶陷阱”促进生物大分子经口服吸收的研究，2018.9.1-2020.8.31

4.主持，上海市自然基金（18ZR1404100），口服pH敏感棒状结构纳米载体靶向炎症性肠病（IBD）的研究，2018.6.1-2021.5.31.

5.主持，上海市自然基金（15ZR1403000），基于荧光共振能量转移效应（FRET）研究脂质体在胃肠道内的转运机制，2015.1-2017.12

6.主持，国家自然科学青年项目（81001405），控制“脂质纳米粒”作为整体单元释放的研究，2011.1-2013.12.

7.主持，上海市科委科技发展基金（1052nm03600），以纳米乳为核的海藻酸纳米囊提高蛋白类药物口服生物利用度的研究，2010.3-2012.6.

8.主持，上海市卫生局青年科研基金，天然酪蛋白纳米胶束作为难溶性药物载体的研究，2013.1-2015.12.

9.子课题负责，上海市科委上药专项（信谊药业牵头），品牌仿制药工艺及质量标准的研究，2010.10-2014.9.

10.子课题负责，上海市科委上药专项（中西药业牵头），阿立哌唑制剂质量标准提升和新工艺研究，2010.10-2014.9.

科研课题（横向）

1.司美格鲁肽口服片剂的研发，100万，2023.1-今

2.嗅吡斯的明缓释片处方与工艺的研究，300万，2018.6-2023.3，共同承担

3.离子液体用于皮肤给药的研究，40万，2016.6-2018,12

4.基于近红外Ⅱ区（NIR-Ⅱ）荧光探针研究载体促进透皮吸收的机制，40万

2019.1-今

5.参与，Novo Nordisk国际合作，脂质体作为胰岛素口服给药系统的研究，10

万欧元，2011.10-2013.12.

代表性论文(*通讯作者, Google Scholar H-index: 51)

1.Qiuyu Li, Wenjuan Liu, Kaiheng Liu, Zirong Dong, Weiwen Kong, Xinrui Lu, Yuning Wei, Wei Wu, Jinlong Yang*, Jianping Qi*. ACS Applied Materials & Interfaces, 2024, In press.

2. Luyu Zhang, Zirong Dong, Shuai Yu, Guangyue Li, Weiwen Kong, Wenjuan Liu, Haisheng He, Yi Lu, Wei Wu, Jianping Qi*. Ionic liquid-based in situ dynamically self-assembled cationic lipid nanocomplexes (CLNs) for enhanced intranasal siRNA delivery. Chinese Chemical Letters, 2023, 109101.

3.Xiying Wu, Min Shen, Xue He, Lianjuan Yang, Jingwen Tan, Hong Yang, Jianping Qi*, Zhongjian Chen*, Qugang Zhu*. Evaluation of the Efficacy and Safety of Ionic Liquids Containing Ketoconazole in Patients with Tinea Pedis：A Randomized Controlled Trial. Bioengineering & Translational Medicine, 2022, e10463

4.Kaiheng Liu, Wenjuan Liu, Zirong Dong, Luyu Zhang, Qiuyu Li, Renjie Zhang, Haisheng He, Yi Lu, Wei Wu, Jianping Qi*. Translation of ionic liquids to be enteric nanoparticles for facilitating oral absorption of cyclosporine A. Bioengineering & Translational Medicine, 2022, e10405

5.Wenjuan Liu, Luyu Zhang, Zirong Dong, Kaiheng Liu, Haisheng H, Yi Lu, Wei Wu, Jianping Qi*. Rod-like mesoporous silica nanoparticles facilitate oral drug delivery via enhanced permeation and retention effect in mucus. Nano Research, 2022, 15, 9243-9252.

6.Luyu Zhang, Zirong Dong, Wenjuan Liu, Xiying Wu, Haisheng He, Yi Lu, Wei Wu, Jianping Qi*. Novel Pharmaceutical Strategies for Enhancing Skin Penetration of Biomacromolecules. Pharmaceuticals, 2022, 15(7): 877.

7.Xiying Wu, Jingjing Xuan, Qin Yu, Wei Wu, Yi Lu, Quangang Zhu, Zhongjian Chen, Jianping Qi*. Converting Tretinoin into Ionic Liquids for Improving Aqueous Solubility and Permeability across Skin. Pharmaceutical Research, 2022, 39(10):2421-2430.

8.Xiying Wu, Quangang Zhu, Zhongjian Chen, Wei Wu, Yi Lu, Jianping Qi*. Ionic liquids as a useful tool for tailoring active pharmaceutical ingredients. Journal of Controlled Release, 2021, 338: 268-283.

9.Quangang Zhu, Zhongjian Chen, Pijush Kumar Paul, Yi Lu, Wei Wu*, Jianping Qi*. Oral delivery of proteins and peptides: Challenges, status quo and future perspectives. Acta Pharmaceutica Sinica B 2021, 11(8):2416-2448.

10.Zirong Dong, Wenjuan Liu, Kaiheng Liu, Yi Lu, Wei Wu, Jianping Qi*, Zhongjian Chen*. Effects on immunization of the physicochemical parameters of particles as vaccine carriers. Drug Discovery Today 2021, 26(7): 1712-1720.

11.Wenjuan Liu, Zirong Dong, Kaiheng Liu, Yi Lu, Wei Wu, Jianping Qi*, Zhongjian Chen*. Targeting strategies of oral nano-delivery systems for treating inflammatory bowel disease. International Journal of Pharmaceutics 2021, 600: 120461.

12.Xiying Wu, Qin Yu, Jing Wu, Tian Li, Ning Ding, Wei Wu, Yi Lu, Quangang Zhu, Zhongjian Chen, Jianping Qi*. Ionic liquids containing ketoconazole improving topical treatment of T. Interdigitale infection by synergistic action. International Journal of Pharmaceutics 2020, 589: 119842.

13.Wenjuan Liu, Dong Li, Zirong Dong, Kaiheng Liu, Haisheng He, Yi Lu, Wei Wu, Qinghua Li, Li Gan, Jianping Qi*. Insight into the in vivo translocation of oral liposomes by fluorescence resonance energy transfer effect. International Journal of Pharmaceutics 2020, 587: 119682.

14.Xiying Wu, Hongmin Zhang, Shuhua He, Qin Yu, Yi Lu, Wei Wu, Ning Ding, Quangang Zhu, Zhongjian Chen, Yuhua Ma, Jianping Qi*. Improving dermal delivery of hyaluronic acid by ionic liquids for attenuating skin dehydration. International Journal Biological Macromolecules 2020, 150: 528-535.

15.Jinlong Yang, Zhirong Dong, Wenjuan Liu, Haisheng He, Wufa Fan, Yi Lu, Wei Wu, Li Gan*, Jianping Qi*. Discriminating against injectable fat emulsions with similar formulation based on water quenching fluorescent probe. Chinese Chemical Letters 2020, 31: 875-879.

16.Yang Li, Xiying Wu, Quangang Zhu, Zhongjian Chen, Yi Lu, Jianping Qi*, Wei Wu. Improving the hypoglycemic effect of insulin via the nasal administration of deep eutectic solvents. International Journal of Pharmaceutics 2019, 569: 118584.

17.Jianping Qi, Xiongwei Hu, Xiaochun Dong, Yi Lu, Huiping Lu, Weili Zhao, Wei Wu*. Towards more accurate bioimaging of drug nanocarriers: turning aggregation-caused quenching into a useful tool. Advanced Drug Delivery Reviews 2019, 143: 206-225.

18.Xiying Wu, Zhongjian Chen, Yang Li, Qin Yu, Yi Lu, Quangang Zhu, Ying Li, Duopeng An, Jianping Qi*, Wei Wu*. Improving dermal delivery of hydrophilic macromolecules by biocompatible ionic liquid based on choline and malic acid. International Journal of Pharmaceutics 2019, 558:380-387.

19.Jie Zhuang, Dandan Wang, Dong Li, Yinqian Yang, Yi Lu, Wei Wu, Wei Wu*, Jianping Qi*. The influence of nanoparticles shape on bilateral exocytosis from Caco-2 cells. Chinese Chemical Letters 2018, 29(12): 1815-1818.

20.Dong Li, Jie Zhuang, Yinqian Yang, Dandan Wang, Jinlong Yang, Haisheng He, Wufa Fan, Amrita Banerjee, Yi Lu, Wu Wei, Li Gan*, Jianping Qi*: Loss of Integrity of Doxorubicin Liposomes during Transcellular Transportation Evidenced by Fluorescence Resonance Energy Transfer Effect. Colloids and Surfaces B: Biointerfaces 2018; 171: 224-232.

21.Jianping Qi, Jie Zhuang, Yi Lu, Wei Wu*: Exploiting or overcoming the “dome trap” for enhanced oral immunization and drug delivery. Journal of Controlled Release 2018; 275: 92-106.

22.Dong Li, Jie Zhuang, Haisheng He, Sifan Jiang, Amrita Banerjee, Yi Lu, Wei Wu, Samir Mitragotri, Li Gan*, Jianping Qi*: Influence of particle geometry on gastrointestinal transit absorption following oral administration. ACS Applied Materials & Interfaces 2017; 9: 42492-42502.

23.Jianping Qi, Jie Zhuang, Yi Lu, Xiaochun Dong, Weili Zhao, Wei Wu*: In vivo fate of lipid-based nanoparticles. Drug discovery today 2017; 22(1): 166-172.

24.Amrita Banerjee¹, Jianping Qi¹（共同第一）, Rohan Gogoi, Jessica Wong, Samir Mitragotri*: Role of nanoparticle size, shape and surface chemistry in oral drug delivery. Journal of Controlled Release 2016; 238:176-185.

25.Zhiqiang Tian, Qin Yu, Yunchang Xie, Li Xiang, Fengqian Li, Yi Lu, Xiaochun Dong, Weili Zhao, Jianping Qi*, Wei Wu*: Controlling Release of Integral Lipid Nanoparticles Based on Osmotic Pump Technology. Pharmaceutical Research 2016; 33(8):1988-1997.

26.Meng Cui, Wei Wu, Lars Hovgaard, Yi Lu, Dawei Chen*, Jianping Qi*: Liposomes containing cholesterol analogues of botanical origin as drug delivery systems to enhance the oral absorption of insulin. International Journal of Pharmaceutics 2015; 489(1-2):277-284.

27.Jianping Qi, Yi Lu, Wei Wu*: Manufacturing Solid Dosage Forms from Bulk Liquids Using the Fluid-bed Drying Technology. Current pharmaceutical design 2015; 21(19):2668-2676.

28.Kai Wang, Jianping Qi*, Tengfei Weng, Zhiqiang Tian, Yi Lu, Kaili Hu, Zongning Yin*, Wei Wu: Enhancement of oral bioavailability of cyclosporine A: comparison of various nanoscale drug delivery systems. International Journal of Nanomedicine 2014; 9:4991-4999.

29.Tengfei Weng, Jianping Qi*, Yi Lu, Kai Wang, Zhiqiang Tian, Kaili Hu, Zongning Yin, Wei Wu: The role of lipid-based nano delivery systems on oral bioavailability enhancement of fenofibrate, a BCS II drug: comparison with fast-release formulations. Journal of Nanobiotechnology 2014; 12(1).

专利

1.戚建平，张露予. 一种原位脂质纳米制剂及其制备方法. 202311081740.8

2.戚建平，刘恺恒，吴伟，卢懿. 提高药物口服生物利用度的载体组合制剂及其制备方法. 202210658751.7

3.戚建平，刘文娟，吴伟，卢懿. 一种促进药物口服吸收的硅纳米载体及其载药体系. 202110687386.8

4.戚建平, 武喜营, 吴伟, 胡弢, 卢懿. 一种离子液体及其制备方法和应用. 202110438588.9.（已授权）

5.戚建平，李洋，吴伟，武喜营，卢懿. 一种鼻腔给药的促渗剂及其应用. 201910613291.4

6.戚建平，武喜营，吴伟，卢懿. 一种促进活性成分渗透皮肤的体系. 201910017977.7（已授权）

7.戚建平，吴伟，李晓阳，卢懿. “一种促进胰岛素口服吸收的外包裹纳米乳”. 201210129636.7 （已授权）

参编著作

1.唐星 主编，《药剂学》第四版（普通高等教育类“十一五”规划教材），中国医药科技出版社，2019.12

2.王东凯 主编，《国家医学教育题库（药学专业题库-药剂学）》，人民卫生出版社，2019.6

3.王岩 主编，《中药药剂学》（普通高等教育制药类“十三五”规划教材），化学工业出版社，2018.9

4.平其能 主编，《中药成分的胃肠转运与剂型设计》，化学工业出版社，2010.7.