姓名：梁停停；博士，讲师 性别：女
出生日期：1991.07；专业：药物化学
电话：15295780890；E-mail：liangting910710@126.com
教育经历
2014.09-2019.12，中国药科大学，药物化学，博士
2010.09-2014.06，中国药科大学，药学，学士
研究方向：小分子药物的设计、合成与活性研究
第一作者及通讯作者论文
1) Liang Tingting1; Cen Lifang1; Wang Junjie; Cheng Ming; Guo Weibo; Wang Wenjie; Yu Chunqiu; Zhang Haifeng; Wang Yuan; Hao Zhongyan; Jin Jiaming; Wu Yaoyao; Jiang Teng; Zhu Qihua*; Xu Yungen*. Discovery of Novel Dual Bruton’s Tyrosine Kinase (BTK) and Janus Kinase 3 (JAK3) Inhibitors as A Promising Strategy for Rheumatoid Arthritis. Bioorg. Med. Chem., 2023, 96: 117354.
2) Niu Linqiang; Cao Qijuan; Zhang Tian; Zhang Yahong; Liang Tingting*; Wang Jianhong*. Simultaneous detection of mitochondrial viscosity and peroxynitrite in livers from subjects with drug-induced fatty liver disease using a novel fluorescent probe. Talanta, 2023, 260: 124591.
3) Liang Tingting1,*; Lu Lu1; Song Xueting; Qi Jianguo; Wang Jianhong*. Combination of microtubule targeting agents with other antineoplastics for cancer treatment. Biochim. Biophys. Acta, Rev. Cancer, 2022, 1877: 188777.
4) Niu Linqiang; Zhang Tian; Zhao Haoran; Dong Haiyang; Zhang Yahong; Liang Tingting*; Wang Jianhong*. Simultaneous imaging of cysteine and viscosity in living cells with sharp contrast fluorescence between red and green by a dual-responsive fluorescence probe. Dyes Pigm., 2022, 206: 110610.
5) Liang Tingting; Zhou Xiaomin; Lu Lu; Dong Haiyang; Zhang Yanan; Xu Yungen; Qi Jianguo*; Zhang Yahong*; Wang Jianhong*. Structure-activity relationships and antiproliferative effects of 1,2,3,4-4H quinoxaline derivatives as tubulin polymerization inhibitors. Bioorg. Chem., 2021, 110: 104793.
6) Liang Tingting1; He Xin1; Ji Dezhong; Wu Huanhuan; Xu Yizhu; Li Yuyan; Wang Zhibin; Xu Yungen*; Zhu Qihua*. Transition metal-free C5 tosyloxylation of 8-aminoquinolines with phenyliodine bistrifluoroacetate and substituted 1,2-disulfonyl hydrazides. Eur. J. Org. Chem., 2019, 2019 (14): 2513-2519.
授权专利
1) 梁停停; 冬海洋; 王建红; 鲁露; 张亚宏; 齐建国. 脲基化合物或其药用盐及其制备方法和用途, 中国, ZL202111681606.2.
2) 王建红; 牛林强; 梁停停; 王佳敏; 罗阳; 曹琦娟; 朱翠娟. 具有七甲川花菁结构的近红外反应型荧光探针及其制备方法和应用, 中国, ZL202010556470.1.
主持项目
1) 河南省科技厅, 河南省重点研发与推广专项（科技攻关）, 212102310316, 抗耐药的微管蛋白秋水仙碱结合位点抑制剂的设计、合成与生物活性研究, 2021-01 至 2022-12, 10万元, 结题, 主持.
2) 河南省教育厅, 河南省高等学校重点科研项目计划, 24A350001, 微管秋水仙碱位点/mTOR双重抑制剂的设计、合成及对耐药非小细胞肺癌活性研究, 2024年度河南省高等学校重点科研项目, 2024-01 至 2025-12, 3万元, 在研, 主持.
副教授
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