1、个人简介:孙晓娟,博士,副教授,2012年毕业于中国科学院遗传与发育生物研究所,获得理学博士学位,2012.06-2013.06在加拿大蒙特利尔大学免疫与癌症研究所(IRIC, UdeM)
Gregory Emery实验室从事于博士后工作,2013年进入河南大学任教
2、主要研究方向:
以模式动物秀丽线虫为平台研究衰老及衰老性疾病的分子机制。
3、承担的研究项目:
(1)国家自然科学基金青年项目(31601091,2017.01-2019.12)
(2)河南省自然科学基金面上项目 (212300410330, 2021.01-2023.12 )
(3)河南大学青年基金交叉项目(2023.8-2025.8)
(4)中州实验室青年提升计划项目(2024TS0104,2024.08-2027.08)
4、已发表论文:
[1] Carlos Zeledon, Xiaojuan Sun, Ce´dric Plutoni, Gregory Emery. The ArfGAP Drongo Promotes Actomyosin Contractility during Collective Cell Migration by Releasing Myosin Phosphatase from the Trailing Edge. Cell Rep. 2019 Sep 17;28(12):3238-3248.e3. doi: 10.1016/j.celrep.2019.08.044.
[2] Liu K, Xing R, Jian Y, Gao Z, Ma X, Sun X, Li Y, Xu M, Wang X, Jing Y1, Guo W, Yang C. WDR91 is a Rab7 effector required for neuronal development. J Cell Biol. 2017 Oct 2;216(10):3307-3321
[3] Xiaojuan Sun, Wei-dong Chen, Yan-dong Wang. DAF-16/FOXO Transcription Factor in Aging and Longevity. Front Pharmacol. 2017 Aug 23; 8:548.
[4] Kai Liu*, Youli Jian*, Xiaojuan Sun*, Chengkui Yang, Zhiyang Gao, Zhili Zhang, Xuezhao Liu, Yang Li, Jing Xu, Yudong Jing, Shohei Mitani, Sudan He, and Chonglin Yang. Negative regulation of phosphatidylinositol 3-phosphate levels in early-to-late endosome conversion J Cell Biol. 2016 Mar 14;212(6):739 (*co-first authors)(当期In focus论文)
[5] Xiaojuan Sun ,Wei-dong Chen ,Yan-dong Wang β-Amyloid: the key peptide in the pathogenesis of Alzheimer's disease,Front Pharmacol. 2015 Sep 30;6:221.
[6] Jing Xu, Xiaojuan Sun, Yudong Jing, Mo Wang, Kai Liu, Youli Jian, Mei Yang, Zhukuan Cheng, Chonglin Yang. MRG-1 is required for genomic integrity in Caenorhabditis elegans germ cells. Cell Res,2012, Jan 3(22(5)):886-902
[7] Mei Yang*, Jianwei Sun*, Xiaojuan Sun, Qinfang Shen, Zhiyang Gao and Chonglin Yang. Caenorhabditis elegans Protein Arginine Methyltransferase PRMT-5 Negatively Regulates DNA Damage-induced Apoptosis. PLoS Genet. 2009 5(6):e1000514
[8] Hui Xiao, Didi Chen, Zhou Fang, Jing Xu, Xiaojuan Sun, Song Song, Jiajia Liu, and Chonglin Yang. Lysosome biogenesis mediated by vps-18 affects apoptotic cell degradation in C. elegans. Molecular Biology of the Cell, 2009, 20:21-31
5、奖励:
2021年河南省优秀科技论文一等奖
2018年河南省优秀科技论文一等奖
2011 18th C.elegans international meeting Financial Aid Award
6、联系方式(邮箱等):sunxiaojuan1020@163.com