科研团队

徐楠，医学博士，副教授，硕士生导师，博士毕业于浙江大学基础医学院。

主要研究方向

代谢性疾病相关的血管病变的发生机制及药物调控研究

承担的研究项目

1.国家自然科学基金青年项目, 3230090251, 2024-01至2026-12,在研,主持

2.河南省自然科学基金青年项目, 222300420120, 2022-01至2023-12,在研,主持

3.河南省博士后基金项目, 2022-12至2024-12,在研,主持

4.河南大学青年交叉基金项目，2024-01至2026-12,在研,主持

已发表论文

1. Jia-Ni Shang , Chen-Ge Yu, Rui Li, Yan Xi, Yue Jenny Jian, *Nan Xu, *Su Chen, The nonautophagic functions of autophagy-related proteins, Autophagy, 2023

2.Nan Xu, Qin Wang, Shan Jiang, Qijing Wang, Weipeng Hu, Suhan Zhou, Liang Zhao, Lanyu Xie, Jianghua Chen, Anton Wellstein, En Yin Lai, Fenofibrate improves vascular endothelial function and contractility in diabetic mice. Redox Biol, 2019;1(20):87-97.

3.Nan Xu, Shan Jiang,Pontus B. Persson,Erik A. G. Persson,En Yin Lai, Andreas Patzak. Reactive oxygen species and renal vascular function. Acta Physiologica. 2020;e13477.

4. Sheng Li , Leilei Zhang, Guoan Zhang, Guoqiang Shangguan, Xitan Hou, Wanglin Duan, Yan Xi , Nan Xu, Bowen Zhang, Junli Dong, Yequan Wang, Wen Cui, Su Chen. A nonautophagic role of ATG5 in regulating cell growth by targeting c-Myc for proteasome-mediated degradation. iScience. 2021;16;24(11)

5.Jiang S, Shui Y, Cui Y, Tang C, Wang X, Qiu X, Hu W, Fei L, Li Y, Zhang S, Zhao L, Xu N, Dong F, Ren X, Liu R, Persson PB, Patzak A, Lai EY, Wei Q, Zheng Z. Gut microbiota dependent trimethylamine N-oxide aggravates angiotensin II-induced hypertension. Redox Biol 2021; 46: 102115.

5. Zhao L, Cao X, Li L, Wang X, Wang Q, Jiang S, Tang C, Zhou S, Xu N, Cui Y, Hu W, Fei L, Zheng Z, Chen L, Schmidt MO, Wei Q, Zhao J, Labes R, Patzak A, Wilcox CS, Fu X, Wellstein A, Lai EY. Acute Kidney Injury Sensitizes the Brain Vasculature to Ang II Constriction via FGFBP1. Hypertension 2020; 76(6): 1924-1934.

6. Suhan Zhou, Shan Jiang, Jie Guo, Nan Xu, Qin Wang, Gensheng Zhang, Liang Zhao, Qin Zhou, Xiaodong Fu, Lingli Li, Andreas Patzak, Michael Hultström, En Yin Lai*, ADAMTS13 protects mice against renal ischemia/reperfusion injury by reducing inflammation and improving endothelial function, Am J Physiol Renal Physiol, 2019; 316(1):134-145.

7.Suping Zhang, Qian Huang, Xiaoxia Cai, Shan Jiang, Nan Xu, Qin Zhou, Xiaoyun Cao, Michael Hultström, Jiong Tian and En Yin Lai, Osthole Ameliorates Renal Fibrosis in Mice by Suppressing Fibroblast Activation and Epithelial-Mesenchymal Transition. Frontiers in Physiology,2018;21(9):1650-1660

8. Hu W, Jiang S, Liao Y, Li J, Dong F, Guo J, Wang X, Fei L, Cui Y, Ren X, Xu N, Zhao L, Patzak A, Persson PB, Zheng Z, Lai EY. High phosphate impairs arterial endothelial function through AMPK-related pathways in mouse resistance arteries. Acta Physiol 2021; 231(4): e13595.

9. Jia Ni Shang , Chen Ge Yu, Rui Li, Yan Xi, Yue Jenny Jian, *Nan Xu, *Su Chen, The nonautophagic functions of autophagy-related proteins，Autophagy, 2023,

联系方式

981279735@qq.com。或xu_nan@henu.edu.cn。